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Synthesis of some new C2 substituted dihydropyrimidines and their electrophysiological evaluation as L-/T-type calcium channel blockers.
Teleb, Mohamed; Rizk, Ola H; Zhang, Fang-Xiong; Fronczek, Frank R; Zamponi, Gerald W; Fahmy, Hesham.
Affiliation
  • Teleb M; Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD 57007, USA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.
  • Rizk OH; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Drug Manufacturing, Pharos University in Alexandria, Alexandria 21311, Egypt.
  • Zhang FX; Department of Physiology & Pharmacology, Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive NW, Calgary T2N 4N1, Canada.
  • Fronczek FR; Department of Chemistry, College of Science, Louisiana State University, Baton Rouge, LA 70803, USA.
  • Zamponi GW; Department of Physiology & Pharmacology, Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive NW, Calgary T2N 4N1, Canada.
  • Fahmy H; Department of Pharmaceutical Sciences, College of Pharmacy, South Dakota State University, Brookings, SD 57007, USA. Electronic address: Hesham.Fahmy@sdstate.edu.
Bioorg Chem ; 88: 102915, 2019 07.
Article in En | MEDLINE | ID: mdl-31005784
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Calcium Channel Blockers / Calcium Channels, L-Type / Calcium Channels, T-Type Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Chem Year: 2019 Type: Article Affiliation country: Egypt
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Calcium Channel Blockers / Calcium Channels, L-Type / Calcium Channels, T-Type Type of study: Prognostic_studies Limits: Humans Language: En Journal: Bioorg Chem Year: 2019 Type: Article Affiliation country: Egypt