TdT expression in germ cell tumours: a possible immunohistochemical cross-reaction and diagnostic pitfall.

Jaconi, Marta; Magni, Fulvio; Raimondo, Francesca; Ponzoni, Maurilio; Chinello, Clizia; Smith, Andrew; Piga, Isabella; Fusco, Nicola; Di Bella, Camillo; Pagni, Fabio

Jaconi, Marta; Magni, Fulvio; Raimondo, Francesca; Ponzoni, Maurilio; Chinello, Clizia; Smith, Andrew; Piga, Isabella; Fusco, Nicola; Di Bella, Camillo; Pagni, Fabio.

Affiliation

Jaconi M; Department of Medicine and Surgery, University Milan Bicocca, Milan, Italy.
Magni F; Department of Medicine and Surgery, University Milan Bicocca, Milan, Italy.
Raimondo F; Department of Medicine and Surgery, University Milan Bicocca, Milan, Italy.
Ponzoni M; Division of Pathology, University San Raffaele, Milan, Italy.
Chinello C; Department of Medicine and Surgery, University Milan Bicocca, Milan, Italy.
Smith A; Department of Medicine and Surgery, University Milan Bicocca, Milan, Italy.
Piga I; Department of Medicine and Surgery, University Milan Bicocca, Milan, Italy.
Fusco N; Division of Pathology, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Di Bella C; Department of Medicine and Surgery, University Milan Bicocca, Milan, Italy.
Pagni F; Department of Medicine and Surgery, University Milan Bicocca, Milan, Italy fabio.pagni@unimib.it.

J Clin Pathol ; 72(8): 536-541, 2019 Aug.

Article in En | MEDLINE | ID: mdl-31055472

Subject(s)

Antibodies, Monoclonal/immunology; Antibody Specificity; Biomarkers, Tumor/analysis; DNA Nucleotidylexotransferase/analysis; Immunohistochemistry; Mediastinal Neoplasms/enzymology; Neoplasms, Germ Cell and Embryonal/enzymology; Ovarian Neoplasms/enzymology; Testicular Neoplasms/enzymology; Biomarkers, Tumor/immunology; Cross Reactions; DNA Nucleotidylexotransferase/immunology; Female; Humans; Italy; Male; Mediastinal Neoplasms/immunology; Mediastinal Neoplasms/pathology; Neoplasms, Germ Cell and Embryonal/immunology; Neoplasms, Germ Cell and Embryonal/pathology; Ovarian Neoplasms/immunology; Ovarian Neoplasms/pathology; Predictive Value of Tests; Reproducibility of Results; Testicular Neoplasms/immunology; Testicular Neoplasms/pathology

Key words

differential diagnosis; genital system; germinal cell tumor; haematopoietic; seminoma; tdt; terminal deoxynucleotidyl transferase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Testicular Neoplasms / Immunohistochemistry / Biomarkers, Tumor / Neoplasms, Germ Cell and Embryonal / DNA Nucleotidylexotransferase / Mediastinal Neoplasms / Antibodies, Monoclonal / Antibody Specificity Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Female / Humans / Male Country/Region as subject: Europa Language: En Journal: J Clin Pathol Year: 2019 Type: Article Affiliation country: Italy

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