ADP heptose, a novel pathogen-associated molecular pattern identified in <i>Helicobacter pylori</i>.

Pfannkuch, Lennart; Hurwitz, Robert; Traulsen, Jan; Sigulla, Janine; Poeschke, Marcella; Matzner, Laura; Kosma, Paul; Schmid, Monika; Meyer, Thomas F

ADP heptose, a novel pathogen-associated molecular pattern identified in Helicobacter pylori.

Pfannkuch, Lennart; Hurwitz, Robert; Traulsen, Jan; Sigulla, Janine; Poeschke, Marcella; Matzner, Laura; Kosma, Paul; Schmid, Monika; Meyer, Thomas F.

Affiliation

Pfannkuch L; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
Hurwitz R; Department of Infectious Diseases and Pulmonary Medicine, Charité, University Hospital Berlin, Berlin, Germany.
Traulsen J; Berlin Institute of Health, Berlin, Germany.
Sigulla J; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
Poeschke M; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
Matzner L; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
Kosma P; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
Schmid M; Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
Meyer TF; Department of Chemistry, University of Natural Resources and Life Sciences-Vienna, Vienna, Austria.

FASEB J ; 33(8): 9087-9099, 2019 08.

Article in En | MEDLINE | ID: mdl-31075211

Subject(s)

Adenosine Diphosphate Sugars/metabolism; Helicobacter pylori/metabolism; Heptoses/metabolism; Pathogen-Associated Molecular Pattern Molecules/metabolism; Adenosine Diphosphate Sugars/chemistry; Adenosine Diphosphate Sugars/immunology; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Cell Line; Epithelial Cells/immunology; Epithelial Cells/metabolism; Epithelial Cells/microbiology; Gene Deletion; Genes, Bacterial; Glycosyltransferases/genetics; Glycosyltransferases/metabolism; Helicobacter pylori/genetics; Helicobacter pylori/immunology; Heptoses/chemistry; Heptoses/immunology; Humans; Immunity, Innate; NF-kappa B/metabolism; Pathogen-Associated Molecular Pattern Molecules/chemistry; Pathogen-Associated Molecular Pattern Molecules/immunology; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry

Key words

ALPK1; LPS; NF-κB; PAMP; TIFA

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenosine Diphosphate Sugars / Helicobacter pylori / Pathogen-Associated Molecular Pattern Molecules / Heptoses Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2019 Type: Article Affiliation country: Germany

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