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Cabotegravir Is Not Associated With Weight Gain in Human Immunodeficiency Virus-uninfected Individuals in HPTN 077.
Landovitz, Raphael J; Zangeneh, Sahar Z; Chau, Gordon; Grinsztejn, Beatriz; Eron, Joseph J; Dawood, Halima; Magnus, Manya; Liu, Albert Y; Panchia, Ravindre; Hosseinipour, Mina C; Kofron, Ryan; Margolis, David A; Rinehart, Alex; Adeyeye, Adeola; Burns, David; McCauley, Marybeth; Cohen, Myron S; Currier, Judith S.
Affiliation
  • Landovitz RJ; Division of Infectious Diseases, Department of Medicine, Center for AIDS Research and Education & Center for HIV Prevention, David Geffen School of Medicine at University of California, Los Angeles.
  • Zangeneh SZ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  • Chau G; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  • Grinsztejn B; Laboratório de HIV, Instituto Nacional de Infectologia Evandro Chagas (INI), Fundação Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Brazil.
  • Eron JJ; Division of Infectious Diseases, University of North Carolina, Chapel Hill.
  • Dawood H; Department of Medicine, University of KwaZulu-Natal, Pietermaritzburg, Durban, South Africa.
  • Magnus M; Department of Epidemiology and Biostatistics, Milken Institute School of Public Health, George Washington University, Washington, DC.
  • Liu AY; Bridge HIV, Population Health Division, San Francisco Department of Public Health, California.
  • Panchia R; Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Soweto, South Africa.
  • Hosseinipour MC; Division of Infectious Diseases, University of North Carolina at Chapel Hill School of Medicine.
  • Kofron R; Division of Infectious Diseases, Department of Medicine, Center for AIDS Research and Education & Center for HIV Prevention, David Geffen School of Medicine at University of California, Los Angeles.
  • Margolis DA; ViiV Healthcare, Research Triangle Park, Durham, North Carolina.
  • Rinehart A; ViiV Healthcare, Research Triangle Park, Durham, North Carolina.
  • Adeyeye A; Division of AIDS, National Institute of Allergy and Infectious Disease, National Institutes of Health, Rockville, Maryland.
  • Burns D; Division of AIDS, National Institute of Allergy and Infectious Disease, National Institutes of Health, Rockville, Maryland.
  • McCauley M; Science Facilitation Department, FHI 360, Washington DC.
  • Cohen MS; Division of Infectious Diseases, University of North Carolina, Chapel Hill.
  • Currier JS; Division of Infectious Diseases, Department of Medicine, Center for AIDS Research and Education & Center for HIV Prevention, David Geffen School of Medicine at University of California, Los Angeles.
Clin Infect Dis ; 70(2): 319-322, 2020 01 02.
Article in En | MEDLINE | ID: mdl-31125395
Studies in human immunodeficiency virus (HIV)-infected individuals suggest excess weight gain with integrase inhibitor-based antiretroviral therapy. The HIV Prevention Trials Network Study 077 evaluated changes in weight and fasting metabolic parameters in HIV-uninfected individuals randomized to cabotegravir or a placebo. No differences between arms were found for change in weight or fasting metabolic parameters overall or for subgroups.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridones / Weight Gain / HIV Infections / Anti-HIV Agents Type of study: Clinical_trials / Risk_factors_studies Limits: Humans Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2020 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridones / Weight Gain / HIV Infections / Anti-HIV Agents Type of study: Clinical_trials / Risk_factors_studies Limits: Humans Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2020 Type: Article