Freehand-SPECT with 99mTc-HDP as tool to guide percutaneous biopsy of skeletal lesions detected on bone scintigraphy. / Freehand-SPECT con 99mTc-HDP como herramienta para guiar la biopsia percutánea de lesiones esqueléticas detectadas en la gammagrafía ósea.
Rev Esp Med Nucl Imagen Mol (Engl Ed)
; 38(4): 218-223, 2019.
Article
in En, Es
| MEDLINE
| ID: mdl-31133492
ABSTRACT
PURPOSE:
To assess the feasibility of using freehand Single Photon Emission Computed Tomography (freehandSPECT) for the identification of technetium-99m-hydroxydiphosphonate (99mTc-HDP) positive bone lesions and to evaluate the possibility of using these imaging data-sets for augmented- and virtual-reality based navigation approaches. MATERIAL ANDMETHODS:
In 20 consecutive patients referred for scintigraphy with 99mTc-HDP, 21 three-dimensional freehandSPECT-images were generated using a handheld gamma camera. Concordance of the two different data sets was ranked. Furthermore, feasibility of segmenting the hotspot of tracer accumulation for navigation purposes was assessed.RESULTS:
In 86% of the cases freehandSPECT images showed good concordance with the corresponding part of the scintigraphic images. In lesions with a signal to background ratio (SBR) >1.36, freehandSPECT provided an automatically segmented reference point for navigation purposes. In 14% of the cases (average SBR 1.82, range 1.0-3.4) freehandSPECT images showed intermediate concordance due to difficult anatomical area or negative bone scintigraphy and could not be used as navigation targets.CONCLUSION:
In this pilot study, in 86% of the cases freehandSPECT demonstrated good concordance with traditional scintigraphy. A lesion with a SBR of 1.36 or more was suitable for navigation. These high-quality freehandSPECT images supported the future exploration navigation strategies, e.g. guided needle biopsies.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biopsy, Needle
/
Bone Diseases
/
Gamma Cameras
/
Tomography, Emission-Computed, Single-Photon
/
Technetium Tc 99m Medronate
/
Image-Guided Biopsy
Type of study:
Clinical_trials
Limits:
Humans
Language:
En
/
Es
Journal:
Rev Esp Med Nucl Imagen Mol (Engl Ed)
Year:
2019
Type:
Article