hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles.

Fischl, Harry; Neve, Jonathan; Wang, Zhiqiao; Patel, Radhika; Louey, Alastair; Tian, Bin; Furger, Andre

Fischl, Harry; Neve, Jonathan; Wang, Zhiqiao; Patel, Radhika; Louey, Alastair; Tian, Bin; Furger, Andre.

Affiliation

Fischl H; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Neve J; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Wang Z; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Patel R; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Louey A; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Tian B; Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School and Rutgers Cancer Institute of New Jersey, Newark, NJ 07103, USA.
Furger A; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.

Nucleic Acids Res ; 47(14): 7580-7591, 2019 08 22.

Article in En | MEDLINE | ID: mdl-31147722

Subject(s)

Alternative Splicing; Heterogeneous-Nuclear Ribonucleoprotein Group C/genetics; Neoplasms/genetics; Polyadenylation; RNA Isoforms/genetics; Aminohydrolases/genetics; Aminohydrolases/metabolism; Cell Line, Transformed; Cell Line, Tumor; Colonic Neoplasms/genetics; Colonic Neoplasms/metabolism; Colonic Neoplasms/pathology; Disease Progression; Formate-Tetrahydrofolate Ligase/genetics; Formate-Tetrahydrofolate Ligase/metabolism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein Group C/metabolism; Humans; Methylenetetrahydrofolate Dehydrogenase (NADP)/genetics; Methylenetetrahydrofolate Dehydrogenase (NADP)/metabolism; Multienzyme Complexes/genetics; Multienzyme Complexes/metabolism; Neoplasms/metabolism; Neoplasms/pathology; Poly A/genetics; Poly A/metabolism; RNA Interference

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alternative Splicing / Polyadenylation / Heterogeneous-Nuclear Ribonucleoprotein Group C / RNA Isoforms / Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2019 Type: Article Affiliation country: United kingdom

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