Valproic acid improves survival and decreases resuscitation requirements in a swine model of prolonged damage control resuscitation.

Williams, Aaron M; Bhatti, Umar F; Biesterveld, Ben E; Graham, Nathan J; Chtraklin, Kiril; Zhou, Jing; Dennahy, Isabel S; Kathawate, Ranganath G; Vercruysse, Claire A; Russo, Rachel M; Li, Yongqing; Alam, Hasan B

Williams, Aaron M; Bhatti, Umar F; Biesterveld, Ben E; Graham, Nathan J; Chtraklin, Kiril; Zhou, Jing; Dennahy, Isabel S; Kathawate, Ranganath G; Vercruysse, Claire A; Russo, Rachel M; Li, Yongqing; Alam, Hasan B.

Affiliation

Williams AM; From the Department of Surgery (A.M.W., U.F.B., B.E.B., N.J.G., K.C., J.Z., I.S.D., R.G.K., C.A.V., R.M.R., Y.L., H.B.A.), University of Michigan Health System, Ann Arbor, Michigan; and Trauma Center, Department of Orthopedics and Traumatology (J.Z.), Peking University People's Hospital, Beijing, China.

J Trauma Acute Care Surg ; 87(2): 393-401, 2019 08.

Article in En | MEDLINE | ID: mdl-31206419

Subject(s)

Resuscitation/methods; Shock, Hemorrhagic/therapy; Valproic Acid/therapeutic use; Animals; Blood Pressure/drug effects; Disease Models, Animal; Female; Heart Rate/drug effects; Hemodynamics/drug effects; Shock, Hemorrhagic/drug therapy; Shock, Hemorrhagic/mortality; Swine; Wounds and Injuries/complications; Wounds and Injuries/drug therapy; Wounds and Injuries/therapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Resuscitation / Shock, Hemorrhagic / Valproic Acid Type of study: Guideline Limits: Animals Language: En Journal: J Trauma Acute Care Surg Year: 2019 Type: Article Affiliation country: China

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