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HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma.
Faião-Flores, Fernanda; Emmons, Michael F; Durante, Michael A; Kinose, Fumi; Saha, Biswarup; Fang, Bin; Koomen, John M; Chellappan, Srikumar P; Maria-Engler, Silvya Stuchi; Rix, Uwe; Licht, Jonathan D; Harbour, J William; Smalley, Keiran S M.
Affiliation
  • Faião-Flores F; The Department of Tumor Biology, The Moffitt Cancer Center & Research Institute, Tampa, Florida.
  • Emmons MF; The Department of Tumor Biology, The Moffitt Cancer Center & Research Institute, Tampa, Florida.
  • Durante MA; Bascom Palmer Eye Institute, Sylvester Comprehensive Cancer Center and Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida.
  • Kinose F; Department of Drug Discovery, The Moffitt Cancer Center & Research Institute, Tampa, Florida.
  • Saha B; The Department of Tumor Biology, The Moffitt Cancer Center & Research Institute, Tampa, Florida.
  • Fang B; Department of Molecular Oncology, The Moffitt Cancer Center & Research Institute, Tampa, Florida.
  • Koomen JM; Department of Molecular Oncology, The Moffitt Cancer Center & Research Institute, Tampa, Florida.
  • Chellappan SP; The Department of Tumor Biology, The Moffitt Cancer Center & Research Institute, Tampa, Florida.
  • Maria-Engler SS; Department of Clinical Chemistry and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
  • Rix U; Department of Drug Discovery, The Moffitt Cancer Center & Research Institute, Tampa, Florida.
  • Licht JD; Division of Hematology & Oncology, Department of Medicine, University of Florida Health Cancer Center, University of Florida, Gainesville, Florida.
  • Harbour JW; Bascom Palmer Eye Institute, Sylvester Comprehensive Cancer Center and Interdisciplinary Stem Cell Institute, University of Miami Miller School of Medicine, Miami, Florida.
  • Smalley KSM; The Department of Tumor Biology, The Moffitt Cancer Center & Research Institute, Tampa, Florida. keiran.smalley@moffitt.org.
Clin Cancer Res ; 25(18): 5686-5701, 2019 09 15.
Article in En | MEDLINE | ID: mdl-31227503
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uveal Neoplasms / Protein Kinase Inhibitors / Histone Deacetylase Inhibitors / Melanoma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uveal Neoplasms / Protein Kinase Inhibitors / Histone Deacetylase Inhibitors / Melanoma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2019 Type: Article