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Ex Vivo Microscopy: A Promising Next-Generation Digital Microscopy Tool for Surgical Pathology Practice.
Krishnamurthy, Savitri; Brown, Jonathan Quincy; Iftimia, Nicusor; Levenson, Richard M; Rajadhyaksha, Milind.
Affiliation
  • Krishnamurthy S; From the Department of Pathology and Laboratory Medicine, The University of Texas, MD Anderson Cancer Center, Houston (Dr Krishnamurthy); Biomedical Engineering, Tulane University, New Orleans, Louisiana (Dr Brown); Physical Sciences Inc, Andover, Massachusetts (Dr Iftimia); the Department of Pathol
  • Brown JQ; From the Department of Pathology and Laboratory Medicine, The University of Texas, MD Anderson Cancer Center, Houston (Dr Krishnamurthy); Biomedical Engineering, Tulane University, New Orleans, Louisiana (Dr Brown); Physical Sciences Inc, Andover, Massachusetts (Dr Iftimia); the Department of Pathol
  • Iftimia N; From the Department of Pathology and Laboratory Medicine, The University of Texas, MD Anderson Cancer Center, Houston (Dr Krishnamurthy); Biomedical Engineering, Tulane University, New Orleans, Louisiana (Dr Brown); Physical Sciences Inc, Andover, Massachusetts (Dr Iftimia); the Department of Pathol
  • Levenson RM; From the Department of Pathology and Laboratory Medicine, The University of Texas, MD Anderson Cancer Center, Houston (Dr Krishnamurthy); Biomedical Engineering, Tulane University, New Orleans, Louisiana (Dr Brown); Physical Sciences Inc, Andover, Massachusetts (Dr Iftimia); the Department of Pathol
  • Rajadhyaksha M; From the Department of Pathology and Laboratory Medicine, The University of Texas, MD Anderson Cancer Center, Houston (Dr Krishnamurthy); Biomedical Engineering, Tulane University, New Orleans, Louisiana (Dr Brown); Physical Sciences Inc, Andover, Massachusetts (Dr Iftimia); the Department of Pathol
Arch Pathol Lab Med ; 143(9): 1058-1068, 2019 09.
Article in En | MEDLINE | ID: mdl-31295016
ABSTRACT
CONTEXT.­ The rapid evolution of optical imaging modalities in recent years has opened the opportunity for ex vivo tissue imaging, which has significant implications for surgical pathology practice. These modalities have promising potential to be used as next-generation digital microscopy tools for examination of fresh tissue, with or without labeling with contrast agents. OBJECTIVE.­ To review the literature regarding various types of ex vivo optical imaging platforms that can generate digital images for tissue recognition with potential for utilization in anatomic pathology clinical practices. DATA SOURCESLiterature relevant to ex vivo tissue imaging obtained from the PubMed database. CONCLUSIONS.­ Ex vivo imaging of tissues can be performed by using various types of optical imaging techniques. These next-generation digital microscopy tools have a promising potential for utilization in surgical pathology practice.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pathology, Surgical / Optical Imaging / Microscopy Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Arch Pathol Lab Med Year: 2019 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pathology, Surgical / Optical Imaging / Microscopy Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Arch Pathol Lab Med Year: 2019 Type: Article