Detrimental effects of chemotherapy on human coronary microvascular function.

Hader, Shelby N; Zinkevich, Natalya; Norwood Toro, Laura E; Kriegel, Alison J; Kong, Amanda; Freed, Julie K; Gutterman, David D; Beyer, Andreas M

Hader, Shelby N; Zinkevich, Natalya; Norwood Toro, Laura E; Kriegel, Alison J; Kong, Amanda; Freed, Julie K; Gutterman, David D; Beyer, Andreas M.

Affiliation

Hader SN; Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Zinkevich N; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
Norwood Toro LE; Department of Health and Medicine, Carroll University, Waukesha, Wisconsin.
Kriegel AJ; Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Kong A; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
Freed JK; Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Gutterman DD; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
Beyer AM; Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.

Am J Physiol Heart Circ Physiol ; 317(4): H705-H710, 2019 10 01.

Article in En | MEDLINE | ID: mdl-31397169

Subject(s)

Antibiotics, Antineoplastic/toxicity; Arterioles/drug effects; Coronary Vessels/drug effects; Doxorubicin/toxicity; Vasodilation/drug effects; Adolescent; Age Factors; Aged; Arterioles/physiopathology; Cardiotoxicity; Case-Control Studies; Child; Child, Preschool; Coronary Vessels/physiopathology; Female; Humans; In Vitro Techniques; Infant; Infant, Newborn; Male; Middle Aged; Vasodilator Agents/pharmacology

Key words

anthracyclines; doxorubicin; endothelial function; flow-mediated dilation; microcirculation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arterioles / Vasodilation / Doxorubicin / Coronary Vessels / Antibiotics, Antineoplastic Type of study: Observational_studies Limits: Adolescent / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged / Newborn Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2019 Type: Article

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