Roles of JAK2 in Aging, Inflammation, Hematopoiesis and Malignant Transformation.

Perner, Florian; Perner, Caroline; Ernst, Thomas; Heidel, Florian H

Perner, Florian; Perner, Caroline; Ernst, Thomas; Heidel, Florian H.

Affiliation

Perner F; Innere Medizin 2, Hämatologie und Onkologie, Universitätsklinikum Jena, 07747 Jena, Germany.
Perner C; Leibniz-Institute on Aging-Fritz Lipmann Institute (FLI), 07745 Jena, Germany.
Ernst T; Dana-Farber Cancer Institute, Department of Pediatric Oncology, Harvard University, Boston, MA 02467, USA.
Heidel FH; Center for Immunology & Inflammatory Diseases, Massachusetts General Hospital, and Harvard Medical School, Boston, 02129 MA, USA.

Cells ; 8(8)2019 08 08.

Article in En | MEDLINE | ID: mdl-31398915

Subject(s)

Aging/metabolism; Hematopoiesis; Inflammation/metabolism; Janus Kinase 2/physiology; Myeloproliferative Disorders/metabolism; Neoplasms/metabolism; Animals; Humans; Mice

Key words

JAK2; Janus-kinase; aging; clonal hematopoiesis (CHIP), myeloproliferative neoplasia (MPN)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Janus Kinase 2 / Hematopoiesis / Inflammation / Myeloproliferative Disorders / Neoplasms Limits: Animals / Humans Language: En Journal: Cells Year: 2019 Type: Article Affiliation country: Germany

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