Therapeutic Drug Monitoring of Olanzapine and Cytochrome P450 Genotyping in Nonsmoking Subjects.

Miroshnichenko, Igor I; Pozhidaev, Ivan V; Ivanova, Svetlana A; Baymeeva, Natalia V

Miroshnichenko, Igor I; Pozhidaev, Ivan V; Ivanova, Svetlana A; Baymeeva, Natalia V.

Affiliation

Miroshnichenko II; Laboratory of Pharmacokinetics, FSBSI, Mental Health Research Center, Moscow, Russian Federation; and.
Pozhidaev IV; Laboratory of Molecular Genetics and Biochemistry, Tomsk National Research Medical Center, Mental Health Research Institute, Russian Academy of Sciences, Tomsk, Russian Federation.
Ivanova SA; Laboratory of Molecular Genetics and Biochemistry, Tomsk National Research Medical Center, Mental Health Research Institute, Russian Academy of Sciences, Tomsk, Russian Federation.
Baymeeva NV; Laboratory of Pharmacokinetics, FSBSI, Mental Health Research Center, Moscow, Russian Federation; and.

Ther Drug Monit ; 42(2): 325-329, 2020 04.

Article in En | MEDLINE | ID: mdl-31425442

Subject(s)

Antipsychotic Agents/pharmacokinetics; Cytochrome P-450 CYP2D6/genetics; Cytochrome P-450 CYP2D6/metabolism; Drug Monitoring/methods; Olanzapine/pharmacokinetics; Adult; Antipsychotic Agents/therapeutic use; Chromatography, Liquid; Genotype; Humans; Male; Non-Smokers; Olanzapine/therapeutic use; Prospective Studies; Psychotic Disorders/drug therapy; Real-Time Polymerase Chain Reaction; Schizophrenia/drug therapy; Tandem Mass Spectrometry; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antipsychotic Agents / Drug Monitoring / Cytochrome P-450 CYP2D6 / Olanzapine Type of study: Guideline / Observational_studies / Risk_factors_studies Limits: Adult / Humans / Male Language: En Journal: Ther Drug Monit Year: 2020 Type: Article

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