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PARP-1 activity (PAR) determines the sensitivity of cervical cancer to olaparib.
Bianchi, Anna; Lopez, Salvatore; Altwerger, Gary; Bellone, Stefania; Bonazzoli, Elena; Zammataro, Luca; Manzano, Aranzazu; Manara, Paola; Perrone, Emanuele; Zeybek, Burak; Han, Chanhee; Menderes, Gulden; Ratner, Elena; Silasi, Dan-Arin; Huang, Gloria S; Azodi, Masoud; Newberg, Justin Y; Pavlick, Dean C; Elvin, Julia; Frampton, Garrett M; Schwartz, Peter E; Santin, Alessandro D.
Affiliation
  • Bianchi A; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Lopez S; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Experimental and Clinical Medicine, Magna Graecia University, Catanzaro 88100, Italy.
  • Altwerger G; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Bellone S; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Bonazzoli E; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Zammataro L; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Manzano A; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Manara P; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Perrone E; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Women's and Children's Health, "Agostino Gemelli" Foundation University Hospital, Catholic University, Rome, Italy.
  • Zeybek B; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Han C; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Menderes G; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Ratner E; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Silasi DA; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Huang GS; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Azodi M; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Newberg JY; Cancer Genomics Research, Foundation Medicine, Cambridge, MA 02141, USA.
  • Pavlick DC; Cancer Genomics Research, Foundation Medicine, Cambridge, MA 02141, USA.
  • Elvin J; Cancer Genomics Research, Foundation Medicine, Cambridge, MA 02141, USA.
  • Frampton GM; Cancer Genomics Research, Foundation Medicine, Cambridge, MA 02141, USA.
  • Schwartz PE; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
  • Santin AD; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: alessandro.santin@yale.edu.
Gynecol Oncol ; 155(1): 144-150, 2019 10.
Article in En | MEDLINE | ID: mdl-31434613
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phthalazines / Piperazines / Uterine Cervical Neoplasms / Poly(ADP-ribose) Polymerase Inhibitors / Poly (ADP-Ribose) Polymerase-1 Type of study: Diagnostic_studies Limits: Adult / Animals / Female / Humans / Middle aged Language: En Journal: Gynecol Oncol Year: 2019 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phthalazines / Piperazines / Uterine Cervical Neoplasms / Poly(ADP-ribose) Polymerase Inhibitors / Poly (ADP-Ribose) Polymerase-1 Type of study: Diagnostic_studies Limits: Adult / Animals / Female / Humans / Middle aged Language: En Journal: Gynecol Oncol Year: 2019 Type: Article Affiliation country: United States