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Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader.
Tovell, Hannah; Testa, Andrea; Zhou, Houjiang; Shpiro, Natalia; Crafter, Claire; Ciulli, Alessio; Alessi, Dario R.
Affiliation
  • Tovell H; Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences , University of Dundee , Dow Street , Dundee DD1 5EH , United Kingdom.
  • Testa A; Division of Biological Chemistry and Drug Discovery, School of Life Sciences , University of Dundee , Dow Street , Dundee , DD1 5EH , United Kingdom.
  • Zhou H; Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences , University of Dundee , Dow Street , Dundee DD1 5EH , United Kingdom.
  • Shpiro N; Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences , University of Dundee , Dow Street , Dundee DD1 5EH , United Kingdom.
  • Crafter C; Bioscience, Research and Early Development, Oncology R&D, AstraZeneca , Cambridge , United Kingdom.
  • Ciulli A; Division of Biological Chemistry and Drug Discovery, School of Life Sciences , University of Dundee , Dow Street , Dundee , DD1 5EH , United Kingdom.
  • Alessi DR; Medical Research Council (MRC) Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences , University of Dundee , Dow Street , Dundee DD1 5EH , United Kingdom.
ACS Chem Biol ; 14(9): 2024-2034, 2019 09 20.
Article in En | MEDLINE | ID: mdl-31461270
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Protein Serine-Threonine Kinases / Dipeptides Type of study: Prognostic_studies Limits: Humans Language: En Journal: ACS Chem Biol Year: 2019 Type: Article Affiliation country: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Protein Serine-Threonine Kinases / Dipeptides Type of study: Prognostic_studies Limits: Humans Language: En Journal: ACS Chem Biol Year: 2019 Type: Article Affiliation country: United kingdom