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FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
Diaz Osterman, Carlos J; Ozmadenci, Duygu; Kleinschmidt, Elizabeth G; Taylor, Kristin N; Barrie, Allison M; Jiang, Shulin; Bean, Lisa M; Sulzmaier, Florian J; Jean, Christine; Tancioni, Isabelle; Anderson, Kristen; Uryu, Sean; Cordasco, Edward A; Li, Jian; Chen, Xiao Lei; Fu, Guo; Ojalill, Marjaana; Rappu, Pekka; Heino, Jyrki; Mark, Adam M; Xu, Guorong; Fisch, Kathleen M; Kolev, Vihren N; Weaver, David T; Pachter, Jonathan A; Gyorffy, Balázs; McHale, Michael T; Connolly, Denise C; Molinolo, Alfredo; Stupack, Dwayne G; Schlaepfer, David D.
Affiliation
  • Diaz Osterman CJ; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Ozmadenci D; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Kleinschmidt EG; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Taylor KN; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Barrie AM; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Jiang S; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Bean LM; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Sulzmaier FJ; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Jean C; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Tancioni I; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Anderson K; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Uryu S; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Cordasco EA; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Li J; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cellular Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Chen XL; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cellular Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Fu G; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cellular Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China.
  • Ojalill M; Department of Biochemistry, University of Turku, Turku, Finland.
  • Rappu P; Department of Biochemistry, University of Turku, Turku, Finland.
  • Heino J; Department of Biochemistry, University of Turku, Turku, Finland.
  • Mark AM; Department of Medicine, UCSD Center for Computational Biology & Bioinformatics, La Jolla, United States.
  • Xu G; Department of Medicine, UCSD Center for Computational Biology & Bioinformatics, La Jolla, United States.
  • Fisch KM; Department of Medicine, UCSD Center for Computational Biology & Bioinformatics, La Jolla, United States.
  • Kolev VN; Verastem Oncology, Needham, United States.
  • Weaver DT; Verastem Oncology, Needham, United States.
  • Pachter JA; Verastem Oncology, Needham, United States.
  • Gyorffy B; Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary.
  • McHale MT; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary.
  • Connolly DC; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
  • Molinolo A; Fox Chase Cancer Center, Philadelphia, United States.
  • Stupack DG; Department of Pathology, Moores UCSD Cancer Center, La Jolla, United States.
  • Schlaepfer DD; Department of Obstetrics, Gynecology and Reproductive Sciences, Moores UCSD Cancer Center, La Jolla, United States.
Elife ; 82019 09 03.
Article in En | MEDLINE | ID: mdl-31478830
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Platinum / Drug Resistance, Neoplasm / Focal Adhesion Kinase 1 / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Elife Year: 2019 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Platinum / Drug Resistance, Neoplasm / Focal Adhesion Kinase 1 / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: Elife Year: 2019 Type: Article Affiliation country: United States