The phenotype of vascular smooth muscle cells co-cultured with endothelial cells is modulated by PDGFR-ß/IQGAP1 signaling in LPS-induced intravascular injury.

Zheng, Xia; Hu, Xiaotong; Zhang, Wang

Zheng, Xia; Hu, Xiaotong; Zhang, Wang.

Affiliation

Zheng X; Department of Critical Care Medicine, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, 310003, P.R. China.
Hu X; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases; The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, P.R. China.
Zhang W; Department of Critical Care Medicine, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, 310003, P.R. China.

Int J Med Sci ; 16(8): 1149-1156, 2019.

Article in En | MEDLINE | ID: mdl-31523178

Subject(s)

Muscle, Smooth, Vascular/cytology; Receptor, Platelet-Derived Growth Factor beta/metabolism; ras GTPase-Activating Proteins/metabolism; Coculture Techniques; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Endothelium, Vascular/cytology; Humans; Lipopolysaccharides/toxicity; Muscle, Smooth, Vascular/drug effects; Phenotype; Sepsis/metabolism; Sepsis/pathology; Signal Transduction; Tumor Necrosis Factor-alpha/metabolism

Key words

Intravascular Injury.; endothelial cells; phenotype; sepsis; smooth muscle cells

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptor, Platelet-Derived Growth Factor beta / Ras GTPase-Activating Proteins / Muscle, Smooth, Vascular Limits: Humans Language: En Journal: Int J Med Sci Journal subject: MEDICINA Year: 2019 Type: Article

Fulltext

XML

PubMed Links

Search on Google