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Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs.
Nakamura, Mari; Shiozawa, Seiji; Tsuboi, Daisuke; Amano, Mutsuki; Watanabe, Hirotaka; Maeda, Sumihiro; Kimura, Taeko; Yoshimatsu, Sho; Kisa, Fumihiko; Karch, Celeste M; Miyasaka, Tomohiro; Takashima, Akihiko; Sahara, Naruhiko; Hisanaga, Shin-Ichi; Ikeuchi, Takeshi; Kaibuchi, Kozo; Okano, Hideyuki.
Affiliation
  • Nakamura M; Department of Physiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan; Department of Biomedical Chemistry, School of International Health, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8654, Japan.
  • Shiozawa S; Department of Physiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. Electronic address: shiozawa@keio.jp.
  • Tsuboi D; Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi 466-8550, Japan.
  • Amano M; Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi 466-8550, Japan.
  • Watanabe H; Department of Physiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Maeda S; Department of Physiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Kimura T; Department of Functional Brain Imaging Research, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 266-8555, Japan.
  • Yoshimatsu S; Department of Physiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Kisa F; Department of Physiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
  • Karch CM; Department of Psychiatry and Hope Center for Neurological Disorders, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Miyasaka T; Department of Neuropathology, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe-shi, Kyoto 610-0394, Japan.
  • Takashima A; Faculty of Science, Gakushuin University, Toshima-ku, Tokyo 171-8588, Japan.
  • Sahara N; Department of Functional Brain Imaging Research, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage, Chiba 266-8555, Japan.
  • Hisanaga SI; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji-shi, Tokyo 192-0397, Japan.
  • Ikeuchi T; Department of Molecular Genetics, Brain Research Institute, Niigata University, 1-757 Asahimachidori, Chuo-ku, Niigata 951-8585, Japan.
  • Kaibuchi K; Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi 466-8550, Japan.
  • Okano H; Department of Physiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. Electronic address: hidokano@keio.jp.
Stem Cell Reports ; 13(4): 684-699, 2019 10 08.
Article in En | MEDLINE | ID: mdl-31543469
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Amino Acid Substitution / Alleles / Induced Pluripotent Stem Cells / Frontotemporal Dementia / Mutation Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Stem Cell Reports Year: 2019 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Amino Acid Substitution / Alleles / Induced Pluripotent Stem Cells / Frontotemporal Dementia / Mutation Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Stem Cell Reports Year: 2019 Type: Article Affiliation country: Japan