Central nervous system vasculitis: advances in diagnosis.
Curr Opin Rheumatol
; 32(1): 41-46, 2020 01.
Article
in En
| MEDLINE
| ID: mdl-31652165
ABSTRACT
PURPOSE OF REVIEW The main purpose of this review is to present advances in diagnostics of central nervous system vasculitis (CNS-V). RECENT FINDINGS:
Progress in molecular technologies and neuroimaging have added formidably to our knowledge of CNS-V. Next-generation sequencing has the promise to enhance our ability to diagnose, interrogate, and track infectious diseases, making this test attractive and capable of avoiding brain biopsy in cases where CNS infections are suspected. Further the continuum of neuroimaging progress has advanced our ability to diagnose CNS-V. Our capability to visualize the vessel wall have added a great value in differentiating inflammatory from noninflammatory vasculopathies. New genetic variations are being exposed with exome and genome sequences which will aid future diagnosis.SUMMARY:
We have witnessed tremendous advances in CNS-V mainly by our ability to rule out mimics. Progress in molecular technologies, neuroimaging and genetic studies will continue to enhance the field further.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vascular Diseases
/
Brain
/
Vasculitis, Central Nervous System
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
En
Journal:
Curr Opin Rheumatol
Journal subject:
REUMATOLOGIA
Year:
2020
Type:
Article
Affiliation country:
United States