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Immunogenicity of Influenza Vaccination in Patients with Cancer Receiving Immune Checkpoint Inhibitors.
Keam, Bhumsuk; Kang, Chang Kyung; Jun, Kang Il; Moon, Song Mi; Suh, Koung Jin; Lee, Dae-Won; Ock, Chan-Young; Kim, Miso; Choi, Yunhee; Lim, Yoojoo; Lee, Kyung-Hun; Kim, Se Hyun; Kim, Tae Min; Kim, Tae-Yong; Oh, Do-Youn; Kim, Dong-Wan; Im, Seock-Ah; Lee, Jong Seok; Kim, Eu Suk; Kim, Hong Bin; Kim, Nam-Joong; Kim, Yu Jung; Park, Wan Beom; Oh, Myoung-Don.
Affiliation
  • Keam B; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Kang CK; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Jun KI; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Moon SM; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Suh KJ; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
  • Lee DW; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
  • Ock CY; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Kim M; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Choi Y; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Lim Y; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Lee KH; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Kim SH; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Kim TM; Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Republic of Korea.
  • Kim TY; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Oh DY; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Kim DW; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Im SA; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Lee JS; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
  • Kim ES; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Kim HB; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Kim NJ; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Kim YJ; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Park WB; Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Oh MD; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
Clin Infect Dis ; 71(2): 422-425, 2020 07 11.
Article in En | MEDLINE | ID: mdl-31680143
ABSTRACT
Among prospectively enrolled adult patients with cancer receiving immune checkpoint inhibitors (ICIs; n = 46) or cytotoxic agents (n = 90), seroprotection and seroconversion rates after seasonal quadrivalent influenza vaccinations were higher with ICI than with cytotoxic chemotherapy. These results support annual influenza vaccinations for cancer patients receiving ICIs. Clinical Trials Registration clinicaltrials.gov (NCT03590808).
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza Vaccines / Influenza, Human / Neoplasms Limits: Adult / Humans Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2020 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza Vaccines / Influenza, Human / Neoplasms Limits: Adult / Humans Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2020 Type: Article