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Ruxolitinib binding to human serum albumin: bioinformatics, biochemical and functional characterization in JAK2V617F+ cell models.
De Marinis, Elisabetta; Ceccherelli, Alessia; Quattrocchi, Alberto; Leboffe, Loris; Polticelli, Fabio; Nervi, Clara; Ascenzi, Paolo.
Affiliation
  • De Marinis E; Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, I-04100, Latina, Italy.
  • Ceccherelli A; Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, I-04100, Latina, Italy.
  • Quattrocchi A; Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, I-04100, Latina, Italy.
  • Leboffe L; Department of Sciences, Roma Tre University, I-00146, Roma, Italy.
  • Polticelli F; Department of Sciences, Roma Tre University, I-00146, Roma, Italy.
  • Nervi C; National Institute of Nuclear Physics, Roma Tre Section, I-00146, Roma, Italy.
  • Ascenzi P; Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, I-04100, Latina, Italy. clara.nervi@uniroma1.it.
Sci Rep ; 9(1): 16379, 2019 11 08.
Article in En | MEDLINE | ID: mdl-31704999
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Enzyme Inhibitors / Mutant Proteins / Janus Kinase 2 / Serum Albumin, Human Type of study: Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2019 Type: Article Affiliation country: Italy
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Enzyme Inhibitors / Mutant Proteins / Janus Kinase 2 / Serum Albumin, Human Type of study: Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2019 Type: Article Affiliation country: Italy