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Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability.
Ericsson, Hans; Nelander, Karin; Heijer, Maria; Kjaer, Magnus; Lindstedt, Eva-Lotte; Albayaty, Muna; Forte, Pablo; Lagerström-Fermér, Maria; Skrtic, Stanko.
Affiliation
  • Ericsson H; Clinical Pharmacology, ADME and AI, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Nelander K; Clinical Pharmacology, ADME and AI, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Heijer M; Clinical Pharmacology Biologics and Bioanalysis, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Kjaer M; Early Biometrics and Statistical Innovation, Data Science & AI, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Lindstedt EL; Research and Early Development, Cardiovascular, Renal and Metabolic, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Albayaty M; Parexel, Early Phase Clinical Unit, Harrow, UK.
  • Forte P; Parexel, Early Phase Clinical Unit, Harrow, UK.
  • Lagerström-Fermér M; Research and Early Development, Cardiovascular, Renal and Metabolic, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Skrtic S; Research and Early Development, Cardiovascular, Renal and Metabolic, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Clin Pharmacol Drug Dev ; 9(3): 411-421, 2020 04.
Article in En | MEDLINE | ID: mdl-31793171
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Food-Drug Interactions / 5-Lipoxygenase-Activating Protein Inhibitors / Rosuvastatin Calcium Type of study: Clinical_trials Limits: Adult / Humans / Male / Middle aged Language: En Journal: Clin Pharmacol Drug Dev Year: 2020 Type: Article Affiliation country: Sweden
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Food-Drug Interactions / 5-Lipoxygenase-Activating Protein Inhibitors / Rosuvastatin Calcium Type of study: Clinical_trials Limits: Adult / Humans / Male / Middle aged Language: En Journal: Clin Pharmacol Drug Dev Year: 2020 Type: Article Affiliation country: Sweden