Lung T-Cell Profile Alterations are Associated with Bronchiolitis Obliterans Syndrome in Cystic Fibrosis Lung Transplant Recipients.

Hayes, Don; Harhay, Michael O; Nicol, Kathleen K; Liyanage, Namal P M; Keller, Brian C; Robinson, Richard T

Hayes, Don; Harhay, Michael O; Nicol, Kathleen K; Liyanage, Namal P M; Keller, Brian C; Robinson, Richard T.

Affiliation

Hayes D; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA. hayes.705@osu.edu.
Harhay MO; Department of Internal Medicine, The Ohio State University College of Medicine, Columbus, OH, USA. hayes.705@osu.edu.
Nicol KK; Department of Surgery, The Ohio State University College of Medicine, Columbus, OH, USA. hayes.705@osu.edu.
Liyanage NPM; Section of Pulmonary Medicine, Nationwide Children's Hospital, Columbus, OH, USA. hayes.705@osu.edu.
Keller BC; The Ohio State University, ED-5022, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA. hayes.705@osu.edu.
Robinson RT; Division of Pulmonary, Allergy and Critical Care and Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Lung ; 198(1): 157-161, 2020 02.

Article in En | MEDLINE | ID: mdl-31807920

Subject(s)

Bronchiolitis Obliterans/immunology; Cystic Fibrosis/surgery; Lung Transplantation; Postoperative Complications/immunology; T-Lymphocyte Subsets/immunology; T-Lymphocytes/immunology; Adolescent; Adult; Bronchiolitis Obliterans/epidemiology; Bronchoalveolar Lavage Fluid/cytology; CD3 Complex/immunology; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/immunology; Case-Control Studies; Female; Graft Rejection/prevention & control; Humans; Immunophenotyping; Immunosuppressive Agents/therapeutic use; Male; Postoperative Complications/epidemiology; Severity of Illness Index; Young Adult

Key words

Bronchiolitis obliterans syndrome; CD4; CD8; Chronic lung allograft dysfunction; Cystic fibrosis; Lung transplant; T-cell

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Postoperative Complications / Bronchiolitis Obliterans / T-Lymphocytes / T-Lymphocyte Subsets / Lung Transplantation / Cystic Fibrosis Type of study: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Lung Year: 2020 Type: Article Affiliation country: United States

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