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[Analysis of Diagnosis and Treatment of 6 Cases of Cerebral Amyloid Angiopathy-related Inflammation].
Zhong, Di; Yang, Tian-Hua; Zhang, Qin; Wu, Bo.
Affiliation
  • Zhong D; Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
  • Yang TH; Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
  • Zhang Q; Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
  • Wu B; Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban ; 51(1): 107-112, 2020 Jan.
Article in Zh | MEDLINE | ID: mdl-31950799
Cerebral amyloid angiopathy associated with inflammation (CAA-ri) is characterized by an inflammatory response to the vascular deposits of ß-amyloid within the brain that is a very rare subtype of cerebral amyloid angiopathy.The most common clinical manifestation of CAA-ri was headache, epilepsy, and cognitive dysfunction. Magnetic resonance imaging (MRI) showed focal or multiple white matter lesions, lobar intracerebral hemorrhage, extensive cortical or subcortical microbleeds. We reported 6 cases of probable CAA-ri diagnosed and treated in our hospital from January 2017 to September 2019 according to the revised diagnostic criteria in 2016.We found that 5 patients also had microbleeds and cortical superficial siderosison T2 and fluid-attenuated inversion recovery (FLAIR), suggesting that if the patients had a long course of disease, older age and heavy microbleeds load, the lesions could be found in the routine MRI, which is a clue for the diagnosis of CAA-ri. Clinicians should attach great importance to this phenomenon, and can further verify by susceptibility weighted imaging (SWI).
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Magnetic Resonance Imaging / Cerebral Amyloid Angiopathy / Inflammation Type of study: Diagnostic_studies / Etiology_studies Limits: Aged / Humans Language: Zh Journal: Sichuan Da Xue Xue Bao Yi Xue Ban Year: 2020 Type: Article Affiliation country: China

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Magnetic Resonance Imaging / Cerebral Amyloid Angiopathy / Inflammation Type of study: Diagnostic_studies / Etiology_studies Limits: Aged / Humans Language: Zh Journal: Sichuan Da Xue Xue Bao Yi Xue Ban Year: 2020 Type: Article Affiliation country: China