Structural, Molecular, and Functional Alterations of the Blood-Brain Barrier during Epileptogenesis and Epilepsy: A Cause, Consequence, or Both?

Löscher, Wolfgang; Friedman, Alon

Löscher, Wolfgang; Friedman, Alon.

Affiliation

Löscher W; Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.
Friedman A; Center of Systems Neuroscience, 30559 Hannover, Germany.

Int J Mol Sci ; 21(2)2020 Jan 16.

Article in En | MEDLINE | ID: mdl-31963328

Subject(s)

Blood-Brain Barrier/metabolism; Epilepsy/metabolism; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism; Albumins/metabolism; Animals; Anticonvulsants/therapeutic use; Epilepsy/drug therapy; Humans; Tight Junctions/drug effects

Key words

P-glycoprotein; albumin; antiepileptic drugs; epileptogenesis; tight junctions

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood-Brain Barrier / Epilepsy Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2020 Type: Article Affiliation country: Germany

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