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Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4.
Juul-Madsen, Kristian; Qvist, Per; Bendtsen, Kirstine L; Langkilde, Annette E; Vestergaard, Bente; Howard, Kenneth A; Dehesa-Etxebeste, Martxel; Paludan, Søren R; Andersen, Gregers Rom; Jensen, Poul Henning; Otzen, Daniel E; Romero-Ramos, Marina; Vorup-Jensen, Thomas.
Affiliation
  • Juul-Madsen K; Biophysical Immunology Laboratory, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Qvist P; Department of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Bendtsen KL; Department of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Langkilde AE; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Vestergaard B; iSEQ, Centre for Integrative Sequencing, Department of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Howard KA; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100 Copenhagen Ø, Denmark.
  • Dehesa-Etxebeste M; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100 Copenhagen Ø, Denmark.
  • Paludan SR; Department of Drug Design and Pharmacology, University of Copenhagen, DK-2100 Copenhagen Ø, Denmark.
  • Andersen GR; Interdisciplinary Nanoscience Center, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Jensen PH; Neuroscience Area, Biodonostia Research Institute, 20014 Donostia, San Sebastian, Spain.
  • Otzen DE; CIBERNED, Instituto de Salud Carlos III, 28029 Madrid, Spain.
  • Romero-Ramos M; Department of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark.
  • Vorup-Jensen T; Department of Molecular Biology and Genetics, Aarhus University, DK-8000 Aarhus C, Denmark.
J Immunol ; 204(5): 1345-1361, 2020 03 01.
Article in En | MEDLINE | ID: mdl-31969389
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Phagosomes / Integrin alphaXbeta2 / Alpha-Synuclein / Protein Aggregation, Pathological / Macrophages Limits: Humans Language: En Journal: J Immunol Year: 2020 Type: Article Affiliation country: Denmark
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Phagosomes / Integrin alphaXbeta2 / Alpha-Synuclein / Protein Aggregation, Pathological / Macrophages Limits: Humans Language: En Journal: J Immunol Year: 2020 Type: Article Affiliation country: Denmark