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Environmental arginine controls multinuclear giant cell metabolism and formation.
Brunner, Julia S; Vulliard, Loan; Hofmann, Melanie; Kieler, Markus; Lercher, Alexander; Vogel, Andrea; Russier, Marion; Brüggenthies, Johanna B; Kerndl, Martina; Saferding, Victoria; Niederreiter, Birgit; Junza, Alexandra; Frauenstein, Annika; Scholtysek, Carina; Mikami, Yohei; Klavins, Kristaps; Krönke, Gerhard; Bergthaler, Andreas; O'Shea, John J; Weichhart, Thomas; Meissner, Felix; Smolen, Josef S; Cheng, Paul; Yanes, Oscar; Menche, Jörg; Murray, Peter J; Sharif, Omar; Blüml, Stephan; Schabbauer, Gernot.
Affiliation
  • Brunner JS; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, 1090, Vienna, Austria.
  • Vulliard L; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, 1090, Vienna, Austria.
  • Hofmann M; CeMM Research Centre for Molecular Medicine of the Austrian Academy of Sciences, 1090, Vienna, Austria.
  • Kieler M; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, 1090, Vienna, Austria.
  • Lercher A; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, 1090, Vienna, Austria.
  • Vogel A; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, 1090, Vienna, Austria.
  • Russier M; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, 1090, Vienna, Austria.
  • Brüggenthies JB; CeMM Research Centre for Molecular Medicine of the Austrian Academy of Sciences, 1090, Vienna, Austria.
  • Kerndl M; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, 1090, Vienna, Austria.
  • Saferding V; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, 1090, Vienna, Austria.
  • Niederreiter B; Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.
  • Junza A; Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.
  • Frauenstein A; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University Vienna, 1090, Vienna, Austria.
  • Scholtysek C; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, 1090, Vienna, Austria.
  • Mikami Y; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, 1090, Vienna, Austria.
  • Klavins K; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, 1090, Vienna, Austria.
  • Krönke G; CIBER of Diabetes and Associated Metabolic Diseases (CIBERDEM), 28029, Madrid, Spain.
  • Bergthaler A; Metabolomics Platform, IISPV, Department of Electronic Engineering, Universitat Rovira i Virgili, 43204, Tarragona, Spain.
  • O'Shea JJ; Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.
  • Weichhart T; Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, 91054, Erlangen, Germany.
  • Meissner F; Molecular Immunology and Inflammation Branch, NIAMS, National Institutes of Health, Bethesda, MD, Bethesda, MD, 20892, USA.
  • Smolen JS; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
  • Cheng P; CeMM Research Centre for Molecular Medicine of the Austrian Academy of Sciences, 1090, Vienna, Austria.
  • Yanes O; Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, 91054, Erlangen, Germany.
  • Menche J; CeMM Research Centre for Molecular Medicine of the Austrian Academy of Sciences, 1090, Vienna, Austria.
  • Murray PJ; Molecular Immunology and Inflammation Branch, NIAMS, National Institutes of Health, Bethesda, MD, Bethesda, MD, 20892, USA.
  • Sharif O; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, 1090, Vienna, Austria.
  • Blüml S; Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.
  • Schabbauer G; Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, 1090, Vienna, Austria.
Nat Commun ; 11(1): 431, 2020 01 22.
Article in En | MEDLINE | ID: mdl-31969567
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginine / Giant Cells Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Type: Article Affiliation country: Austria
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginine / Giant Cells Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Type: Article Affiliation country: Austria