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First-in-human phase I clinical trial of the NY-ESO-1 protein cancer vaccine with NOD2 and TLR9 stimulants in patients with NY-ESO-1-expressing refractory solid tumors.
Ishihara, Mikiya; Tono, Yasutaka; Miyahara, Yoshihiro; Muraoka, Daisuke; Harada, Naozumi; Kageyama, Shinichi; Sasaki, Takeshi; Hori, Yasuhide; Soga, Norihito; Uchida, Katsunori; Shiraishi, Taizo; Sato, Eiichi; Kanda, Hideki; Mizuno, Toshiro; Webster, Gill A; Ikeda, Hiroaki; Katayama, Naoyuki; Sugimura, Yoshiki; Shiku, Hiroshi.
Affiliation
  • Ishihara M; Department of Medical Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. mishihara@clin.medic.mie-u.ac.jp.
  • Tono Y; Department of Medical Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
  • Miyahara Y; Department of Personalized Cancer Immunotherapy, Mie University Graduate School of Medicine, 1577 Kurimamachiya-cho, Tsu, Mie, 514-8507, Japan.
  • Muraoka D; Department of Oncology, Nagasaki University Graduate School of Biomedical Sciences, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan.
  • Harada N; United Immunity, Co., Ltd., Room220, Mie University Campus Incubator, 1577 Kurimamachiya-cho, Tsu, Mie, 514-8507, Japan.
  • Kageyama S; Department of Immuno-Gene Therapy, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
  • Sasaki T; Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
  • Hori Y; Kameyama Nephro-Urologic Clinic, 1488-215 Sakaemachi, Kameyama, Mie, 519-0111, Japan.
  • Soga N; Department of Urology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi, 464-8681, Japan.
  • Uchida K; Department of Pathology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
  • Shiraishi T; Department of Pathology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
  • Sato E; Department of Pathology, Institute of Medical Science (Medical Research Center), Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
  • Kanda H; Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
  • Mizuno T; Department of Medical Oncology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
  • Webster GA; Innate Immunotherapeutics, Melbourne, VIC, 3051, Australia.
  • Ikeda H; Department of Oncology, Nagasaki University Graduate School of Biomedical Sciences, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan.
  • Katayama N; Department of Hematology and Oncology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
  • Sugimura Y; Department of Nephro-Urologic Surgery and Andrology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
  • Shiku H; Department of Personalized Cancer Immunotherapy, Mie University Graduate School of Medicine, 1577 Kurimamachiya-cho, Tsu, Mie, 514-8507, Japan. shiku@clin.medic.mie-u.ac.jp.
Cancer Immunol Immunother ; 69(4): 663-675, 2020 Apr.
Article in En | MEDLINE | ID: mdl-31980914
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cancer Vaccines / Toll-Like Receptor 9 / Nod2 Signaling Adaptor Protein / Membrane Proteins / Antigens, Neoplasm / Neoplasms Limits: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Cancer Immunol Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2020 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cancer Vaccines / Toll-Like Receptor 9 / Nod2 Signaling Adaptor Protein / Membrane Proteins / Antigens, Neoplasm / Neoplasms Limits: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Cancer Immunol Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2020 Type: Article Affiliation country: Japan