Retrospective analysis of the association between tooth loss and dementia: a population-based matched case-control study.
Community Dent Health
; 37(1): 59-64, 2020 Feb 27.
Article
in En
| MEDLINE
| ID: mdl-32031342
ABSTRACT
OBJECTIVE:
To clarify the association between multiple tooth loss and dementia. BASIC RESEARCHDESIGN:
Case-control study based on the claims data from National Health Insurance Research Database (NHIRD). Patients were divided into two groups the dementia groups and non-dementia group. For each case patient, one control patient was randomly selected and frequency matched by age (per 5 years) and sex. The case group comprised patients newly diagnosed with dementia, and the index date was the the date of dementia diagnosis, which became the baseline for comorbidity and age calculations.RESULTS:
Among the 43,026 individuals, patients with dementia had a significantly higher extraction density at ages 60-69 (p ⟨ 0.0001) and 70-79 (p = 0.04) years compared with control patients.CONCLUSIONS:
This population-based retrospective study demonstrated an association between tooth loss and dementia. Patients in Taiwan with more tooth extraction experience are likely to have an increased risk of dementia.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tooth Loss
/
Dementia
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Aged
/
Humans
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
Community Dent Health
Journal subject:
ODONTOLOGIA
/
SAUDE PUBLICA
Year:
2020
Type:
Article
Affiliation country:
Taiwan