Label-Free Detection of Zeptomol miRNA via Peptide Nucleic Acid Hybridization Using Novel Cyclic Voltammetry Method.

Takase, Shintaro; Miyagawa, Kouta; Ikeda, Hisafumi

Takase, Shintaro; Miyagawa, Kouta; Ikeda, Hisafumi.

Affiliation

Takase S; New Business Management Division, Management Planning H.Q., YOKOWO CO. LTD., 5-11, Takinogawa 7-Chome, Kita-ku, Tokyo 114-8515, Japan.
Miyagawa K; New Business Management Division, Management Planning H.Q., YOKOWO CO. LTD., 5-11, Takinogawa 7-Chome, Kita-ku, Tokyo 114-8515, Japan.
Ikeda H; Department of Environmental Science and Education, Faculty of Home Economics, Tokyo Kasei University, 1-18-1 Kaga, Itabashi City, Tokyo 173-8602, Japan.

Sensors (Basel) ; 20(3)2020 Feb 04.

Article in En | MEDLINE | ID: mdl-32033197

Subject(s)

Electric Capacitance; Electrochemistry/methods; MicroRNAs/blood; Nucleic Acid Hybridization; Peptide Nucleic Acids/chemistry; Biosensing Techniques/methods; Electric Conductivity; Electrodes; Hexanols/chemistry; Humans; Ions; Microelectrodes; Microscopy, Electron, Scanning; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Sulfhydryl Compounds/chemistry

Key words

140-zeptomol sensitivity; PCR-less; cyclic voltammograms; label-free; new hybridization system; new ion-channel sensor model; ΔE measurements

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Nucleic Acids / Electric Capacitance / MicroRNAs / Electrochemistry / Nucleic Acid Hybridization Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Sensors (Basel) Year: 2020 Type: Article Affiliation country: Japan

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