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Effect of Intravenous Interferon ß-1a on Death and Days Free From Mechanical Ventilation Among Patients With Moderate to Severe Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.
Ranieri, V Marco; Pettilä, Ville; Karvonen, Matti K; Jalkanen, Juho; Nightingale, Peter; Brealey, David; Mancebo, Jordi; Ferrer, Ricard; Mercat, Alain; Patroniti, Nicolò; Quintel, Michael; Vincent, Jean-Louis; Okkonen, Marjatta; Meziani, Ferhat; Bellani, Giacomo; MacCallum, Niall; Creteur, Jacques; Kluge, Stefan; Artigas-Raventos, Antonio; Maksimow, Mikael; Piippo, Ilse; Elima, Kati; Jalkanen, Sirpa; Jalkanen, Markku; Bellingan, Geoff.
Affiliation
  • Ranieri VM; Alma Mater Studiorum-Università di Bologna, Dipartimento di Scienze Mediche e Chirurgiche, Anesthesia and Intensive Care Medicine, Policlinico di Sant'Orsola, Bologna, Italy.
  • Pettilä V; Division of Intensive Care, Department of Anesthesiology, Intensive Care, and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Karvonen MK; Faron Pharmaceuticals Ltd, Turku, Finland.
  • Jalkanen J; Faron Pharmaceuticals Ltd, Turku, Finland.
  • Nightingale P; Manchester University NHS Foundation Trust, Wythenshawe Hospital, Manchester, United Kingdom.
  • Brealey D; Critical Care, University College London Hospitals, NHS Foundation Trust and National Institute for Health Research Biomedical Research Centre at University College London Hospitals NHS Foundation Trust and University College London, London, United Kingdom.
  • Mancebo J; Department of Intensive Care, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain.
  • Ferrer R; Department of Intensive Care/SODIR Research Group-VHIR Hospital Universitari Vall d'Hebron UCI, Barcelona, Spain.
  • Mercat A; Médecine Intensive-Réanimation CHU d'Angers, Université d'Angers, Angers, France.
  • Patroniti N; Dipartimento di scienze diagnostiche e integrate, Università degli studi di Genova, Genova, Italy.
  • Quintel M; Anesthesiology and Operative Intensive Care Medicine, Universitätsmedizin Göttingen, Göttingen, Germany.
  • Vincent JL; Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
  • Okkonen M; Division of Intensive Care, Department of Anesthesiology, Intensive Care, and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Meziani F; Université de Strasbourg (UNISTRA), Faculté de Médecine, Hôpitaux universitaires de Strasbourg, Nouvel Hôpital Civil, Service de réanimation, Strasbourg, France.
  • Bellani G; Azienda Ospedaliera San Gerardo, Milan, Italy.
  • MacCallum N; Critical Care, University College London Hospitals, NHS Foundation Trust and National Institute for Health Research Biomedical Research Centre at University College London Hospitals NHS Foundation Trust and University College London, London, United Kingdom.
  • Creteur J; Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
  • Kluge S; Department of Intensive Care, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Artigas-Raventos A; Corporacion Sanitaria Universitaria Parc Tauli CIBER Enfermedades Respiratorias Autonomous University of Barcelona, Sabadell, Spain.
  • Maksimow M; Faron Pharmaceuticals Ltd, Turku, Finland.
  • Piippo I; Faron Pharmaceuticals Ltd, Turku, Finland.
  • Elima K; Medicity research Laboratory, University of Turku, Turku, Finland.
  • Jalkanen S; Medicity research Laboratory, University of Turku, Turku, Finland.
  • Jalkanen M; Faron Pharmaceuticals Ltd, Turku, Finland.
  • Bellingan G; Critical Care, University College London Hospitals, NHS Foundation Trust and National Institute for Health Research Biomedical Research Centre at University College London Hospitals NHS Foundation Trust and University College London, London, United Kingdom.
JAMA ; 323(8): 725-733, 2020 02 25.
Article in En | MEDLINE | ID: mdl-32065831
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Distress Syndrome / Adjuvants, Immunologic / Interferon beta-1a Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2020 Type: Article Affiliation country: Italy
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Distress Syndrome / Adjuvants, Immunologic / Interferon beta-1a Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2020 Type: Article Affiliation country: Italy