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Leptin promotes methionine adenosyltransferase 2A expression in hepatic stellate cells by the downregulation of E2F-4 via the ß-catenin pathway.
Cheng, Fangyun; Su, Shengyan; Zhu, Xiaofei; Jia, Xin; Tian, Haimeng; Zhai, Xuguang; Guan, Wei; Zhou, Yajun.
Affiliation
  • Cheng F; Department of Biochemistry & Molecular Biology, Medical College, Nantong University, Nantong, China.
  • Su S; Department of Biochemistry & Molecular Biology, Medical College, Nantong University, Nantong, China.
  • Zhu X; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, China.
  • Jia X; Department of Biochemistry & Molecular Biology, Medical College, Nantong University, Nantong, China.
  • Tian H; Department of Biochemistry & Molecular Biology, Medical College, Nantong University, Nantong, China.
  • Zhai X; Department of Biochemistry & Molecular Biology, Medical College, Nantong University, Nantong, China.
  • Guan W; Department of Pharmacology, School of Pharmacy, Nantong University, Nantong, China.
  • Zhou Y; Department of Biochemistry & Molecular Biology, Medical College, Nantong University, Nantong, China.
FASEB J ; 34(4): 5578-5589, 2020 04.
Article in En | MEDLINE | ID: mdl-32108965
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Leptin / Beta Catenin / E2F4 Transcription Factor / Hepatic Stellate Cells / Liver Cirrhosis / Methionine Adenosyltransferase Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2020 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Leptin / Beta Catenin / E2F4 Transcription Factor / Hepatic Stellate Cells / Liver Cirrhosis / Methionine Adenosyltransferase Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2020 Type: Article Affiliation country: China