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Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy.
Geck, Renee C; Foley, Jackson R; Murray Stewart, Tracy; Asara, John M; Casero, Robert A; Toker, Alex.
Affiliation
  • Geck RC; Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215.
  • Foley JR; Harvard Medical School, Boston, Massachusetts 02115.
  • Murray Stewart T; Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287.
  • Asara JM; Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287.
  • Casero RA; Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215.
  • Toker A; Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287.
J Biol Chem ; 295(19): 6263-6277, 2020 05 08.
Article in En | MEDLINE | ID: mdl-32139506

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ornithine Decarboxylase / Biogenic Polyamines / Eflornithine / Cytotoxins / Triple Negative Breast Neoplasms / Ornithine Decarboxylase Inhibitors / Neoplasm Proteins Limits: Female / Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ornithine Decarboxylase / Biogenic Polyamines / Eflornithine / Cytotoxins / Triple Negative Breast Neoplasms / Ornithine Decarboxylase Inhibitors / Neoplasm Proteins Limits: Female / Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article