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Cyclosporine a directly affects human and mouse b cell migration in vitro by disrupting a hIF-1 αdependent, o2 sensing, molecular switch.
Hilchey, Shannon P; Palshikar, Mukta G; Emo, Jason A; Li, Dongmei; Garigen, Jessica; Wang, Jiong; Mendelson, Eric S; Cipolla, Valentina; Thakar, Juilee; Zand, Martin S.
Affiliation
  • Hilchey SP; University of Rochester Medical CenterDivision of Nephrology, 601 Elmwood Ave., Rochester, 14642, NY, USA.
  • Palshikar MG; University of RochesterBiophysics, Structural, and Computational Biology Program, 601 Elmwood Ave. - Box 675, Rochester, 14642, NY, USA.
  • Emo JA; University of Rochester Medical CenterDivision of Nephrology, 601 Elmwood Ave., Rochester, 14642, NY, USA.
  • Li D; University of RochesterClinical and Translational Science Institute, 265 Crittenden Blvd., Rochester, 14642, NY, USA.
  • Garigen J; University of RochesterClinical and Translational Science Institute, 265 Crittenden Blvd., Rochester, 14642, NY, USA.
  • Wang J; University of Rochester Medical CenterDivision of Nephrology, 601 Elmwood Ave., Rochester, 14642, NY, USA.
  • Mendelson ES; University of Rochester Medical CenterDivision of Nephrology, 601 Elmwood Ave., Rochester, 14642, NY, USA.
  • Cipolla V; University of Rochester Medical CenterDivision of Nephrology, 601 Elmwood Ave., Rochester, 14642, NY, USA.
  • Thakar J; University of RochesterDepartment of Microbiology and Immunology, 601 Elmwood Ave - Box 672, Rochester, 14642, NY, USA.
  • Zand MS; University of RochesterDepartment of Biostatistics and Computational Biology, 265 Crittenden Blvd., Rochester, 14642, NY, USA.
BMC Immunol ; 21(1): 13, 2020 03 18.
Article in En | MEDLINE | ID: mdl-32183695
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Cyclosporine / Germinal Center / Agammaglobulinemia / Hypoxia-Inducible Factor 1, alpha Subunit / Immunosuppressive Agents / Hypoxia Type of study: Etiology_studies Limits: Animals / Female / Humans Language: En Journal: BMC Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Cyclosporine / Germinal Center / Agammaglobulinemia / Hypoxia-Inducible Factor 1, alpha Subunit / Immunosuppressive Agents / Hypoxia Type of study: Etiology_studies Limits: Animals / Female / Humans Language: En Journal: BMC Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2020 Type: Article Affiliation country: United States