Subcutaneous tanezumab for osteoarthritis of the hip or knee: efficacy and safety results from a 24-week randomised phase III study with a 24-week follow-up period.

Berenbaum, Francis; Blanco, Francisco J; Guermazi, Ali; Miki, Kenji; Yamabe, Takaharu; Viktrup, Lars; Junor, Rod; Carey, William; Brown, Mark T; West, Christine R; Verburg, Kenneth M

Berenbaum, Francis; Blanco, Francisco J; Guermazi, Ali; Miki, Kenji; Yamabe, Takaharu; Viktrup, Lars; Junor, Rod; Carey, William; Brown, Mark T; West, Christine R; Verburg, Kenneth M.

Affiliation

Berenbaum F; Department of Rheumatology, Sorbonne Université, INSERM CRSA, AP-HP Hopital Saint Antoine, Paris, France francis.berenbaum@aphp.fr.
Blanco FJ; Servicio de Reumatología, INIBC-Complejo Hospitalario Universitario A Coruña, La Coruña, Spain.
Guermazi A; Department of Radiology, Boston University School of Medicine, Boston, Massachusetts, USA.
Miki K; Faculty of Health Science, Osaka Yukioka College of Health Science, Hayaishi Hospital, Osaka, Japan.
Yamabe T; Pfizer Inc, Groton, Connecticut, USA.
Viktrup L; Eli Lilly and Company, Indianapolis, Indiana, USA.
Junor R; Pfizer Ltd, Tadworth, UK.
Carey W; Pfizer Ltd, Tadworth, UK.
Brown MT; Pfizer Inc, Groton, Connecticut, USA.
West CR; Pfizer Inc, Groton, Connecticut, USA.
Verburg KM; Pfizer Inc, Groton, Connecticut, USA.

Ann Rheum Dis ; 79(6): 800-810, 2020 06.

Article in En | MEDLINE | ID: mdl-32234715

Subject(s)

Analgesics/therapeutic use; Antibodies, Monoclonal, Humanized/therapeutic use; Musculoskeletal Pain/drug therapy; Osteoarthritis, Hip/drug therapy; Osteoarthritis, Knee/drug therapy; Adult; Aged; Aged, 80 and over; Analgesics/adverse effects; Antibodies, Monoclonal, Humanized/adverse effects; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypesthesia/chemically induced; Injections, Subcutaneous; Male; Middle Aged; Musculoskeletal Pain/etiology; Osteoarthritis, Hip/complications; Osteoarthritis, Hip/surgery; Osteoarthritis, Knee/complications; Osteoarthritis, Knee/surgery; Pain Measurement; Paresthesia/chemically induced; Physical Functional Performance

Key words

analgesics; knee osteoarthritis; osteoarthritis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis, Hip / Osteoarthritis, Knee / Musculoskeletal Pain / Antibodies, Monoclonal, Humanized / Analgesics Type of study: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Ann Rheum Dis Year: 2020 Type: Article Affiliation country: France

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