Exploring the Relevance of Senotherapeutics for the Current SARS-CoV-2 Emergency and Similar Future Global Health Threats.

Malavolta, Marco; Giacconi, Robertina; Brunetti, Dario; Provinciali, Mauro; Maggi, Fabrizio

Malavolta, Marco; Giacconi, Robertina; Brunetti, Dario; Provinciali, Mauro; Maggi, Fabrizio.

Affiliation

Malavolta M; Advanced Technology Center for Aging Research, IRCCS INRCA, 60121 Ancona, Italy.
Giacconi R; Advanced Technology Center for Aging Research, IRCCS INRCA, 60121 Ancona, Italy.
Brunetti D; Mitochondrial Medicine Laboratory, Department of Medical Biotechnology and Translational Medicine, University of Milan, 20133 Milan, Italy.
Provinciali M; Advanced Technology Center for Aging Research, IRCCS INRCA, 60121 Ancona, Italy.
Maggi F; Department of Translational Research, University of Pisa, 56126 Pisa, Italy.

Cells ; 9(4)2020 04 08.

Article in En | MEDLINE | ID: mdl-32276453

Subject(s)

Aging/immunology; Coronavirus Infections/drug therapy; Coronavirus Infections/immunology; Global Health/trends; Pneumonia, Viral/drug therapy; Pneumonia, Viral/immunology; Anti-Infective Agents/standards; Anti-Infective Agents/therapeutic use; Azithromycin/therapeutic use; COVID-19; Cellular Senescence/immunology; Humans; Interleukin-6/immunology; Nitriles; Pandemics; Pyrazoles/therapeutic use; Pyrimidines

Key words

SASP inhibitors; cellular senescence; extracellular vesicles; inflammation; mitochondria; senolytics; senoptotics; viral infection

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Viral / Aging / Global Health / Coronavirus Infections Limits: Humans Language: En Journal: Cells Year: 2020 Type: Article Affiliation country: Italy

Fulltext

XML

PubMed Links

Search on Google