Integrin &#945;vß3-Akt signalling plays a role in radioresistance of melanoma.

Im, Hyuntaik; Lee, Jeeyong; Ryu, Kwon-Yul; Yi, Jae Youn

Integrin αvß3-Akt signalling plays a role in radioresistance of melanoma.

Im, Hyuntaik; Lee, Jeeyong; Ryu, Kwon-Yul; Yi, Jae Youn.

Affiliation

Im H; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
Lee J; Department of Life Science, University of Seoul, Seoul, Korea.
Ryu KY; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.
Yi JY; Department of Life Science, University of Seoul, Seoul, Korea.

Exp Dermatol ; 29(6): 562-569, 2020 06.

Article in En | MEDLINE | ID: mdl-32298492

Subject(s)

Integrin alphaVbeta3/metabolism; Melanoma/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Radiation Tolerance; Skin Neoplasms/metabolism; Cell Line, Tumor; Cell Survival; Gamma Rays; Heterocyclic Compounds, 3-Ring/pharmacology; Humans; Integrin alphaVbeta3/antagonists & inhibitors; Melanoma/radiotherapy; Proto-Oncogene Proteins c-akt/antagonists & inhibitors; Signal Transduction; Skin Neoplasms/radiotherapy; Snake Venoms/pharmacology

Key words

MK-2206; SK-Mel28; SK-Mel5; cilengitide; Î³-irradiation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation Tolerance / Skin Neoplasms / Integrin alphaVbeta3 / Proto-Oncogene Proteins c-akt / Melanoma Limits: Humans Language: En Journal: Exp Dermatol Journal subject: DERMATOLOGIA Year: 2020 Type: Article

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