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PRMT5 silencing selectively affects MTAP-deleted mesothelioma: In vitro evidence of a novel promising approach.
Barbarino, Marcella; Cesari, Daniele; Bottaro, Maria; Luzzi, Luca; Namagerdi, Asadoor; Bertolino, Franca Maria; Bellan, Cristiana; Proietti, Fabrizio; Somma, Pasquale; Micheli, Mariacarolina; de Santi, Maria Margherita; Guazzo, Raffaella; Mutti, Luciano; Pirtoli, Luigi; Paladini, Piero; Indovina, Paola; Giordano, Antonio.
Affiliation
  • Barbarino M; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Cesari D; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania.
  • Bottaro M; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Luzzi L; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Namagerdi A; Department of Medicine, Surgery and Neurosciences, Siena University Hospital, Siena, Italy.
  • Bertolino FM; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Bellan C; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Proietti F; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Somma P; Agilent Technologies, Milan, Italy.
  • Micheli M; Anatomy and Pathology Unit, Ospedale dei Colli, AORN, "Monaldi", Naples, Italy.
  • de Santi MM; Anatomy and Pathology Unit, Ospedale dei Colli, AORN, "Monaldi", Naples, Italy.
  • Guazzo R; Department of Medicine, Surgery and Neurosciences, Siena University Hospital, Siena, Italy.
  • Mutti L; Department of Medicine, Surgery and Neurosciences, Siena University Hospital, Siena, Italy.
  • Pirtoli L; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania.
  • Paladini P; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania.
  • Indovina P; Department of Medicine, Surgery and Neurosciences, Siena University Hospital, Siena, Italy.
  • Giordano A; Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania.
J Cell Mol Med ; 24(10): 5565-5577, 2020 05.
Article in En | MEDLINE | ID: mdl-32301278
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Arginine N-Methyltransferases / Gene Expression Regulation, Neoplastic / Purine-Nucleoside Phosphorylase / Gene Deletion / Gene Silencing / Mesothelioma Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2020 Type: Article Affiliation country: Italy
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein-Arginine N-Methyltransferases / Gene Expression Regulation, Neoplastic / Purine-Nucleoside Phosphorylase / Gene Deletion / Gene Silencing / Mesothelioma Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2020 Type: Article Affiliation country: Italy