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Whole-slide image analysis of the tumor microenvironment identifies low B-cell content as a predictor of adverse outcome in patients with advanced-stage classical Hodgkin lymphoma treated with BEACOPP.
Jachimowicz, Ron Daniel; Pieper, Luise; Reinke, Sarah; Gontarewicz, Artur; Plütschow, Annette; Haverkamp, Heinz; Frauenfeld, Leonie; Fend, Falko; Overkamp, Mathis; Jochims, Franziska; Thorns, Christoph; Leo Hansmann, Martin; Möller, Peter; Rosenwald, Andreas; Stein, Harald; Reinhardt, Hans Christian; Borchmann, Peter; von Tresckow, Bastian; Engert, Andreas; Klapper, Wolfram.
Affiliation
  • Jachimowicz RD; University of Cologne,University Hospital Cologne, Cologne, Germany.
  • Pieper L; University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany.
  • Reinke S; University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany.
  • Gontarewicz A; University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany.
  • Plütschow A; University of Cologneand University Hospital Cologne, German Hodgkin Study Group, Germany.
  • Haverkamp H; University of Cologneand University Hospital Cologne, German Hodgkin Study Group, Germany.
  • Frauenfeld L; Department of Pathology, University of Tübingen, Germany.
  • Fend F; Department of Pathology, University of Tübingen, Germany.
  • Overkamp M; Department of Pathology, University of Tübingen, Germany.
  • Jochims F; University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany.
  • Thorns C; Department of Pathology, University Hospital Schleswig-Holstein, University of Lübeck, Germany.
  • Leo Hansmann M; Department of Pathology, University Hospital Frankfurt, Germany.
  • Möller P; Department of Pathology, University Hospital Ulm, Germany.
  • Rosenwald A; Institute of Pathology, University of Würzburg, Comprehensive Cancer Center Mainfranken, Germany.
  • Stein H; Pathodiagnostik, Berlin, Germany.
  • Reinhardt HC; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, Germany.
  • Borchmann P; University of Cologne, German Hodgkin Study Group, Cologne, Germany.
  • von Tresckow B; University of Cologne, German Hodgkin Study Group, Cologne, Germany.
  • Engert A; University of Cologne, German Hodgkin Study Group, Cologne, Germany.
  • Klapper W; University Hospital Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany.
Haematologica ; 106(6): 1684-1692, 2021 06 01.
Article in En | MEDLINE | ID: mdl-32381573
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hodgkin Disease Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Haematologica Year: 2021 Type: Article Affiliation country: Germany
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hodgkin Disease Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Haematologica Year: 2021 Type: Article Affiliation country: Germany