Sulforaphane ameliorates serum starvation-induced muscle atrophy via activation of the Nrf2 pathway in cultured C2C12 cells.

Moon, Jae Yun; Kim, Da Jeong; Kim, Hye Sun

Moon, Jae Yun; Kim, Da Jeong; Kim, Hye Sun.

Affiliation

Moon JY; Department of Biological Science, Ajou University, Suwon, Korea.
Kim DJ; Department of Biological Science, Ajou University, Suwon, Korea.
Kim HS; Department of Biological Science, Ajou University, Suwon, Korea.

Cell Biol Int ; 44(9): 1831-1839, 2020 Sep.

Article in En | MEDLINE | ID: mdl-32401383

Subject(s)

Isothiocyanates/pharmacology; Muscular Atrophy/metabolism; NF-E2-Related Factor 2/metabolism; Sulfoxides/pharmacology; Animals; Antioxidants/pharmacology; Apoptosis/drug effects; Cell Line; Cell Survival/drug effects; Heme Oxygenase-1/metabolism; Isothiocyanates/metabolism; Kelch-Like ECH-Associated Protein 1/metabolism; Membrane Proteins/metabolism; Mice; Muscle Fibers, Skeletal/metabolism; Muscle Fibers, Skeletal/physiology; Muscular Atrophy/drug therapy; NF-E2-Related Factor 2/genetics; NF-E2-Related Factor 2/physiology; Oxidative Stress/physiology; Reactive Oxygen Species/metabolism; Signal Transduction/drug effects; Sulfoxides/metabolism; Vitamin K 3/adverse effects; Vitamin K 3/pharmacology

Key words

C2C12; HO-1; Nrf2; muscle atrophy; oxidative stress; sulforaphane

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfoxides / Muscular Atrophy / Isothiocyanates / NF-E2-Related Factor 2 Limits: Animals Language: En Journal: Cell Biol Int Year: 2020 Type: Article

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