Effects of Single Mutations on Protein Stability Are Gaussian Distributed.

Razban, Rostam M; Shakhnovich, Eugene I

Razban, Rostam M; Shakhnovich, Eugene I.

Affiliation

Razban RM; Department of Chemistry & Chemical Biology, Harvard University, Cambridge, Massachusetts.
Shakhnovich EI; Department of Chemistry & Chemical Biology, Harvard University, Cambridge, Massachusetts. Electronic address: shakhnovich@chemistry.harvard.edu.

Biophys J ; 118(12): 2872-2878, 2020 06 16.

Article in En | MEDLINE | ID: mdl-32416078

Subject(s)

Amino Acids; Proteins; Mutation; Normal Distribution; Protein Stability; Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Amino Acids Language: En Journal: Biophys J Year: 2020 Type: Article

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Amino Acids Language: En Journal: Biophys J Year: 2020 Type: Article