Hyaluronan Degradation Promotes Cancer via Hippo-YAP Signaling: An Intervention Point for Cancer Therapy.

Ooki, Takuya; Hatakeyama, Masanori

Ooki, Takuya; Hatakeyama, Masanori.

Affiliation

Ooki T; Division of Microbiology, Graduate School of Medicine, the University of Tokyo, Tokyo, 113-0033, Japan.
Hatakeyama M; Division of Microbiology, Graduate School of Medicine, the University of Tokyo, Tokyo, 113-0033, Japan.

Bioessays ; 42(7): e2000005, 2020 07.

Article in En | MEDLINE | ID: mdl-32449813

Subject(s)

Hyaluronic Acid; Neoplasms; Hippo Signaling Pathway; Humans; Neoplasms/drug therapy; Protein Serine-Threonine Kinases/metabolism; Signal Transduction; Tumor Microenvironment

Key words

CD44; Hippo signal; cancer microenvironment; extracellular matrix; hyaluronan; hyaluronidase; yes-associated protein (YAP)

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hyaluronic Acid / Neoplasms Limits: Humans Language: En Journal: Bioessays Journal subject: BIOLOGIA / BIOLOGIA MOLECULAR Year: 2020 Type: Article Affiliation country: Japan

Fulltext

XML

PubMed Links

Search on Google