Increased incidence of systemic serious viral infections in patients with inflammatory bowel disease associates with active disease and use of thiopurines.

Wisniewski, Andrew; Kirchgesner, Julien; Seksik, Philippe; Landman, Cécilia; Bourrier, Anne; Nion-Larmurier, Isabelle; Marteau, Philippe; Cosnes, Jacques; Sokol, Harry; Beaugerie, Laurent

Wisniewski, Andrew; Kirchgesner, Julien; Seksik, Philippe; Landman, Cécilia; Bourrier, Anne; Nion-Larmurier, Isabelle; Marteau, Philippe; Cosnes, Jacques; Sokol, Harry; Beaugerie, Laurent.

Affiliation

Wisniewski A; Gastroenterology Department of Charles-Lemoyne hospital, Université de Sherbrooke, Montréal, Canada.
Kirchgesner J; Department of Gastroenterology, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Sorbonne Université, AP-HP Hôpital Saint-Antoine, Paris, France
Seksik P; Department of Gastroenterology, INSERM, Centre de recherche Saint-Antoine, Sorbonne Université, AP-HP Hôpital Saint-Antoine, Paris, France
Landman C; Department of Gastroenterology, AP-HP Hôpital Saint-Antoine, Paris, France
Bourrier A; Department of Gastroenterology, INSERM, Centre de recherche Saint-Antoine, Sorbonne Université, AP-HP Hôpital Saint-Antoine, Paris, France
Nion-Larmurier I; Department of Gastroenterology, AP-HP Hôpital Saint-Antoine, Paris, France
Marteau P; Department of Liver Diseases, INSERM, Centre de recherche Saint-Antoine, Sorbonne Université, AP-HP Hôpital Saint-Antoine, Paris, France
Cosnes J; Department of Gastroenterology, AP-HP Hôpital Saint-Antoine, Paris, France
Sokol H; Department of Liver Diseases, INSERM, Centre de recherche Saint-Antoine, Sorbonne Université, AP-HP Hôpital Saint-Antoine, Paris, France
Beaugerie L; Department of Gastroenterology, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Sorbonne Université, AP-HP Hôpital Saint-Antoine, Paris, France

United European Gastroenterol J ; 8(3): 303-313, 2020 04.

Article in En | MEDLINE | ID: mdl-32529821

Subject(s)

Azathioprine/adverse effects; Herpesviridae Infections/epidemiology; Immunosuppressive Agents/adverse effects; Inflammatory Bowel Diseases/drug therapy; Adolescent; Adult; Aged; Case-Control Studies; Cost of Illness; Cytomegalovirus/immunology; Cytomegalovirus/isolation & purification; Female; France/epidemiology; Herpesviridae Infections/diagnosis; Herpesviridae Infections/immunology; Herpesviridae Infections/virology; Herpesvirus 3, Human/immunology; Herpesvirus 3, Human/isolation & purification; Herpesvirus 4, Human/immunology; Herpesvirus 4, Human/isolation & purification; Hospitalization/statistics & numerical data; Humans; Incidence; Inflammatory Bowel Diseases/diagnosis; Inflammatory Bowel Diseases/immunology; Male; Middle Aged; Prospective Studies; Risk Assessment/statistics & numerical data; Risk Factors; Severity of Illness Index; Simplexvirus/immunology; Simplexvirus/isolation & purification; Young Adult

Key words

Viral infections; immune-suppressive therapy; thiopurines; cytomegalovirus; EpsteinBarr virus; hemophagocytic lymphohistiocytosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azathioprine / Inflammatory Bowel Diseases / Herpesviridae Infections / Immunosuppressive Agents Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: United European Gastroenterol J Year: 2020 Type: Article Affiliation country: Canada

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