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Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.
Dong, Yunxia; Hong, Wei; Tang, Zhiyin; Gao, Yan; Wu, Xiuying; Liu, Hongtao.
Affiliation
  • Dong Y; Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, China.
  • Hong W; Department of Ultrasound, The Third Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, China.
  • Tang Z; Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, China.
  • Gao Y; Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, China.
  • Wu X; Department of Anesthesiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou, China.
  • Liu H; Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, China.
Mediators Inflamm ; 2020: 5458061, 2020.
Article in En | MEDLINE | ID: mdl-32655312

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Receptors, Growth Factor / Brain-Derived Neurotrophic Factor / Dexmedetomidine / RhoA GTP-Binding Protein / Receptor, trkB / Sevoflurane / Nerve Tissue Proteins Limits: Animals Language: En Journal: Mediators Inflamm Journal subject: BIOQUIMICA / PATOLOGIA Year: 2020 Type: Article Affiliation country: China

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Receptors, Growth Factor / Brain-Derived Neurotrophic Factor / Dexmedetomidine / RhoA GTP-Binding Protein / Receptor, trkB / Sevoflurane / Nerve Tissue Proteins Limits: Animals Language: En Journal: Mediators Inflamm Journal subject: BIOQUIMICA / PATOLOGIA Year: 2020 Type: Article Affiliation country: China