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Th17 lymphocyte-dependent degradation of joint cartilage by synovial fibroblasts in a humanized mouse model of arthritis and reversal by secukinumab.
Margheri, Francesca; Maggi, Laura; Biagioni, Alessio; Chillà, Anastasia; Laurenzana, Anna; Bianchini, Francesca; Bani, Daniele; Capone, Manuela; Mazzoni, Alessio; Rossi, Maria Caterina; Liotta, Francesco; Cosmi, Lorenzo; Giani, Teresa; Cimaz, Rolando; Fibbi, Gabriella; Annunziato, Francesco; Del Rosso, Mario.
Affiliation
  • Margheri F; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
  • Maggi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Biagioni A; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
  • Chillà A; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
  • Laurenzana A; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
  • Bianchini F; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
  • Bani D; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Capone M; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Mazzoni A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Rossi MC; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Liotta F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Cosmi L; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Giani T; AOU Meyer, Florence, Italy.
  • Cimaz R; Department of Clinical Sciences and Community Health, University of Milano, Milan, Italy.
  • Fibbi G; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
  • Annunziato F; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Del Rosso M; Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
Eur J Immunol ; 51(1): 220-230, 2021 01.
Article in En | MEDLINE | ID: mdl-32691428
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Juvenile / Cartilage, Articular / Th17 Cells / Antibodies, Monoclonal, Humanized Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Animals / Child / Child, preschool / Humans Language: En Journal: Eur J Immunol Year: 2021 Type: Article Affiliation country: Italy
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Juvenile / Cartilage, Articular / Th17 Cells / Antibodies, Monoclonal, Humanized Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Animals / Child / Child, preschool / Humans Language: En Journal: Eur J Immunol Year: 2021 Type: Article Affiliation country: Italy