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Interactive tool to create adjustable anatomical atlases for mouse brain imaging.
Sack, Markus; Zheng, Lei; Gass, Natalia; Ende, Gabriele; Sartorius, Alexander; Weber-Fahr, Wolfgang.
Affiliation
  • Sack M; Department of Neuroimaging, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. markus.sack@zi-mannheim.de.
  • Zheng L; Research Group Translational Imaging, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. markus.sack@zi-mannheim.de.
  • Gass N; Research Group Translational Imaging, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
  • Ende G; Data Analysis and Modeling in Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Sartorius A; Department of Neuroimaging, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
  • Weber-Fahr W; Research Group Translational Imaging, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
MAGMA ; 34(2): 183-187, 2021 Apr.
Article in En | MEDLINE | ID: mdl-32696290
ABSTRACT

OBJECTIVE:

Brain atlases are important research tools enabling researchers to focus their investigations on specific anatomically defined brain regions and are used in many MRI applications, e.g. in fMRI, morphometry, whole brain spectroscopy, et cetera. Despite their extensive use and numerous versions they usually consist of predefined rigid brain regions with a given level of detail often degrading them to a non-ideal tool in special research topics.

RESULT:

To overcome this intrinsic weakness we present a graphical user interface application which allows researchers to easily create mouse brain atlases with an adjustable user-defined level of detail and coverage to match specific research questions.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Magnetic Resonance Imaging Limits: Animals Language: En Journal: MAGMA Journal subject: DIAGNOSTICO POR IMAGEM Year: 2021 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Magnetic Resonance Imaging Limits: Animals Language: En Journal: MAGMA Journal subject: DIAGNOSTICO POR IMAGEM Year: 2021 Type: Article Affiliation country: Germany