ADAM-Mediated Signalling Pathways in Gastrointestinal Cancer Formation.

Schumacher, Neele; Rose-John, Stefan; Schmidt-Arras, Dirk

Schumacher, Neele; Rose-John, Stefan; Schmidt-Arras, Dirk.

Affiliation

Schumacher N; Institute of Biochemistry, Christian-Albrechts-University, 24118 Kiel, Germany.
Rose-John S; Institute of Biochemistry, Christian-Albrechts-University, 24118 Kiel, Germany.
Schmidt-Arras D; Institute of Biochemistry, Christian-Albrechts-University, 24118 Kiel, Germany.

Int J Mol Sci ; 21(14)2020 Jul 20.

Article in En | MEDLINE | ID: mdl-32698506

Subject(s)

ADAM Proteins/metabolism; Gastrointestinal Neoplasms/metabolism; Signal Transduction; ADAM Proteins/antagonists & inhibitors; Animals; Cytokines/metabolism; Drug Discovery; Enzyme Inhibitors/pharmacology; ErbB Receptors/metabolism; Gastrointestinal Neoplasms/drug therapy; Gastrointestinal Neoplasms/pathology; Humans; Molecular Targeted Therapy; Signal Transduction/drug effects; Tumor Microenvironment/drug effects

Key words

ADAM; EGFR; IL-6; Notch; protease; tumour micro-environment

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / ADAM Proteins / Gastrointestinal Neoplasms Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2020 Type: Article Affiliation country: Germany

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