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Chronic stress induces formation of stress granules and pathological TDP-43 aggregates in human ALS fibroblasts and iPSC-motoneurons.
Ratti, Antonia; Gumina, Valentina; Lenzi, Paola; Bossolasco, Patrizia; Fulceri, Federica; Volpe, Clara; Bardelli, Donatella; Pregnolato, Francesca; Maraschi, AnnaMaria; Fornai, Francesco; Silani, Vincenzo; Colombrita, Claudia.
Affiliation
  • Ratti A; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Piazzale Brescia 20, 20149 Milan, Italy; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Via Fratelli Cervi 93, 20090 Segrate, Milan, Italy. Elec
  • Gumina V; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Piazzale Brescia 20, 20149 Milan, Italy.
  • Lenzi P; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, via Roma 55, 56126 Pisa, Italy. Electronic address: paola.lenzi@med.unipi.it.
  • Bossolasco P; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Piazzale Brescia 20, 20149 Milan, Italy.
  • Fulceri F; Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 55, Pisa 56126, Italy. Electronic address: federica.fulceri@unipi.it.
  • Volpe C; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Piazzale Brescia 20, 20149 Milan, Italy; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Via Fratelli Cervi 93, 20090 Segrate, Milan, Italy. Elec
  • Bardelli D; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Piazzale Brescia 20, 20149 Milan, Italy; "Aldo Ravelli" Center for Neurotechnology and Experimental Brain Therapeutics, Università degli Studi di Milano, Via A. di Rudinì 8, 20142 Milan, Italy.
  • Pregnolato F; Istituto Auxologico Italiano, IRCCS, Immunorheumatology Research Laboratory, Via Zucchi 18, 20095 Cusano Milanino, Milan, Italy.
  • Maraschi A; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Piazzale Brescia 20, 20149 Milan, Italy.
  • Fornai F; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, via Roma 55, 56126 Pisa, Italy; I.R.C.C.S. Neuromed, via Atinense 18, 86077 Pozzilli (IS), Italy. Electronic address: francesco.fornai@neuromed.it.
  • Silani V; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Piazzale Brescia 20, 20149 Milan, Italy; "Aldo Ravelli" Center for Neurotechnology and Experimental Brain Therapeutics, Università degli Studi di Milano, Via A. di Rudinì 8, 20142 Milan, Italy; D
  • Colombrita C; Istituto Auxologico Italiano, IRCCS, Department of Neurology-Stroke Unit and Laboratory of Neuroscience, Piazzale Brescia 20, 20149 Milan, Italy. Electronic address: c.colombrita@auxologico.it.
Neurobiol Dis ; 145: 105051, 2020 11.
Article in En | MEDLINE | ID: mdl-32827688
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / DNA-Binding Proteins / Fibroblasts / Amyotrophic Lateral Sclerosis / Motor Neurons Limits: Humans Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2020 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / DNA-Binding Proteins / Fibroblasts / Amyotrophic Lateral Sclerosis / Motor Neurons Limits: Humans Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2020 Type: Article