Medical treatment of tuberous sclerosis-related epilepsy.
Childs Nerv Syst
; 36(10): 2511-2517, 2020 10.
Article
in En
| MEDLINE
| ID: mdl-32829444
ABSTRACT
Epilepsy is one of the most frequent CNS manifestations of tuberous sclerosis, and for most patients, it is the major debilitating factor. In up to 70% of the cases, the epilepsy is refractory and usually associated with significant behavioral as well as developmental consequences. Therefore, controlling seizures is one of the biggest medical and surgical challenges. Understanding the cellular mechanism involved in the disease empowered targeted research aimed toward early intervention in the epileptogenicity process. In this review, we present an update on the pharmacological treatments in tuberous sclerosis-related epilepsy.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tuberous Sclerosis
/
Epilepsy
Type of study:
Etiology_studies
Limits:
Humans
Language:
En
Journal:
Childs Nerv Syst
Journal subject:
NEUROLOGIA
/
PEDIATRIA
Year:
2020
Type:
Article
Affiliation country:
Israel