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Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH.
Sica, Michela; Pellecchia, Annamaria; De Angioletti, Maria; Caocci, Giovanni; Nannelli, Caterina; La Nasa, Giorgio; Luzzatto, Lucio; Notaro, Rosario.
Affiliation
  • Sica M; Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory-Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.
  • Pellecchia A; Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory-Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.
  • De Angioletti M; Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory-Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.
  • Caocci G; Institute of Chemistry of Organometallic Compounds (ICCOM), National Council of Research, Sesto Fiorentino, Italy.
  • Nannelli C; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
  • La Nasa G; Hematology and BMT Center, Businco Hospital, Cagliari, Italy.
  • Luzzatto L; Laboratory of Cancer Genetics and Gene Transfer, Core Research Laboratory-Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.
  • Notaro R; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Blood ; 136(26): 3082-3085, 2020 12 24.
Article in En | MEDLINE | ID: mdl-32845970
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Complement System Proteins / Oxidative Stress / Erythrocytes / Antibodies, Monoclonal, Humanized / Glucosephosphate Dehydrogenase Deficiency / Hemoglobinuria, Paroxysmal Limits: Adult / Female / Humans Language: En Journal: Blood Year: 2020 Type: Article Affiliation country: Italy
Fulltext
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XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Complement System Proteins / Oxidative Stress / Erythrocytes / Antibodies, Monoclonal, Humanized / Glucosephosphate Dehydrogenase Deficiency / Hemoglobinuria, Paroxysmal Limits: Adult / Female / Humans Language: En Journal: Blood Year: 2020 Type: Article Affiliation country: Italy