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Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism.
Ågren, Richard; Zeberg, Hugo; Stepniewski, Tomasz Maciej; Free, R Benjamin; Reilly, Sean W; Luedtke, Robert R; Århem, Peter; Ciruela, Francisco; Sibley, David R; Mach, Robert H; Selent, Jana; Nilsson, Johanna; Sahlholm, Kristoffer.
Affiliation
  • Ågren R; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
  • Zeberg H; Department of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
  • Stepniewski TM; Department of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
  • Free RB; Research Programme on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), 08003 Barcelona, Spain.
  • Reilly SW; InterAx Biotech AG, PARK innovAARE, 5234 Villigen, Switzerland.
  • Luedtke RR; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Warsaw 02-089, Poland.
  • Århem P; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, Intramural Research Program, National Institutes of Health, Bethesda, Maryland 20892-3723, United States.
  • Ciruela F; Department of Radiology, Division of Nuclear Medicine and Clinical Molecular Imaging, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, United States.
  • Sibley DR; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, Texas 76107, United States.
  • Mach RH; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
  • Selent J; Department of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
  • Nilsson J; Pharmacology Unit, Department of Pathology and Experimental Therapeutics, Faculty of Medicine and Health Sciences, Institute of Neurosciences, University of Barcelona, L'Hospitalet de Llobregat 08907, Spain.
  • Sahlholm K; Neuropharmacology and Pain Group, Neuroscience Program, Institut d'Investigació Biomèdica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat 08907, Spain.
ACS Chem Neurosci ; 11(19): 3130-3143, 2020 10 07.
Article in En | MEDLINE | ID: mdl-32865974

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dopamine / Receptors, Dopamine D2 Language: En Journal: ACS Chem Neurosci Year: 2020 Type: Article Affiliation country: Sweden

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dopamine / Receptors, Dopamine D2 Language: En Journal: ACS Chem Neurosci Year: 2020 Type: Article Affiliation country: Sweden